Lyon and Eintracht Frankfurt secured first-leg victories Wednesday in the Europa League round of 16.
In Spain, all the goals came in the opening 32 minutes as Frankfurt won 2-1 at Real Betis.
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Frankfurt's Rafael Santos Borre misses a scoring chance on a penalty shoot during the Europa League, round of 16, first leg soccer match between Betis and Eintracht Frankfurt at the Benito Villamarin stadium in Seville, Spain, Wednesday, March 9, 2022. (AP PhotoAngel Fernandez)
Frankfurt's Filip Kostic, celebrates after scoring his side's first goal during the Europa League, round of 16, first leg soccer match between Betis and Eintracht Frankfurt at the Benito Villamarin stadium in Seville, Spain, Wednesday, March 9, 2022. (AP PhotoAngel Fernandez)
Lyon's Lucas Paqueta celebrates at the end of the Europa League round of 16, first leg, soccer match between FC Porto and Lyon at the Dragao stadium in Porto, Portugal, Wednesday, March 9, 2022. Lyon won 1-0. (AP PhotoLuis Vieira)
Lyon's Lucas Paqueta, with his head bandaged, poses for photos with fans at the end of the Europa League round of 16, first leg, soccer match between FC Porto and Lyon at the Dragao stadium in Porto, Portugal, Wednesday, March 9, 2022. Lyon won 1-0. (AP PhotoLuis Vieira)
Porto's Mehdi Taremi vies for the ball with Lyon's Tanguy Ndombele, 2nd left, during the Europa League round of 16, first leg, soccer match between FC Porto and Lyon at the Dragao stadium in Porto, Portugal, Wednesday, March 9, 2022. (AP PhotoLuis Vieira)
Video screens and publicity boards show the word "Peace" during the Europa League round of 16, first leg, soccer match between FC Porto and Lyon at the Dragao stadium in Porto, Portugal, Wednesday, March 9, 2022. (AP PhotoLuis Vieira)
Filip Kostić scored the opener for the German side in the 14th by shooting over goalkeeper Claudio Bravo. It was canceled out by Nabil Fekir curling in a shot on the half-hour but Daichi Kamada slotted Frankfurt back in front two minutes later from close range.
Frankfurt's Rafael Santos Borre misses a scoring chance on a penalty shoot during the Europa League, round of 16, first leg soccer match between Betis and Eintracht Frankfurt at the Benito Villamarin stadium in Seville, Spain, Wednesday, March 9, 2022. (AP PhotoAngel Fernandez)
Bravo prevented the visitors from taking a bigger advantage back to Germany for next week's second leg by saving a penalty in the second half from Rafael Borré.
In Portugal, Lucas Paquetá was set up by Moussa Dembele’s pass in the 59th minute to clinch Lyon’s 1-0 win at Porto.
The remaining last-16 first legs are on Thursday, including Barcelona hosting Galatasaray.
Frankfurt's Filip Kostic, celebrates after scoring his side's first goal during the Europa League, round of 16, first leg soccer match between Betis and Eintracht Frankfurt at the Benito Villamarin stadium in Seville, Spain, Wednesday, March 9, 2022. (AP PhotoAngel Fernandez)
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Lyon's Lucas Paqueta celebrates at the end of the Europa League round of 16, first leg, soccer match between FC Porto and Lyon at the Dragao stadium in Porto, Portugal, Wednesday, March 9, 2022. Lyon won 1-0. (AP PhotoLuis Vieira)
Lyon's Lucas Paqueta, with his head bandaged, poses for photos with fans at the end of the Europa League round of 16, first leg, soccer match between FC Porto and Lyon at the Dragao stadium in Porto, Portugal, Wednesday, March 9, 2022. Lyon won 1-0. (AP PhotoLuis Vieira)
Porto's Mehdi Taremi vies for the ball with Lyon's Tanguy Ndombele, 2nd left, during the Europa League round of 16, first leg, soccer match between FC Porto and Lyon at the Dragao stadium in Porto, Portugal, Wednesday, March 9, 2022. (AP PhotoLuis Vieira)
Video screens and publicity boards show the word "Peace" during the Europa League round of 16, first leg, soccer match between FC Porto and Lyon at the Dragao stadium in Porto, Portugal, Wednesday, March 9, 2022. (AP PhotoLuis Vieira)