SEOUL, South Korea, Nov. 25, 2024 /PRNewswire/ -- J INTS BIO announced research findings on its innovative brain tumor treatment, 'JIN-001,' developed in collaboration with MD Anderson Cancer Center, at the 2024 Society of Neuro-Oncology (SNO) Annual Meeting in Texas, USA. MD Anderson is a globally renowned cancer research institution, and J INTS BIO has partnered with it since 2021 to advance this groundbreaking therapy.
JIN-001: Aiming to Revolutionize Brain Tumor Treatment
'JIN-001' targets glioblastoma (GBM) cells by significantly enhancing the efficacy of radiation therapy and chemotherapy. As a selective inhibitor of HSP90 (Heat Shock Protein 90), its primary advantage lies in its ability to cross the blood-brain barrier (BBB), which typically hinders therapeutic agents from reaching the brain. While the BBB serves as a protective mechanism for the brain, it also presents a major obstacle for drug delivery. JIN-001 overcomes this limitation, directly attacking brain tumors and addressing the low permeability issue of existing drugs.
The study also highlighted that JIN-001 demonstrated promising results when combined with standard therapies such as Radiation Therapy and Temozolomide, effectively suppressing tumor cell growth and inducing apoptosis (programmed cell death).
JIN-001: Pioneering Future Clinical Developments
Based on these promising findings, J INTS BIO plans to accelerate preclinical trials for JIN-001. The company intends to incorporate CRISPR gene-editing technology to identify the functional roles of specific genetic factors in treatment resistance, paving the way for precision medicine strategies. CRISPR-based techniques allow targeted modulation of gene expression, helping to predict and better understand tumor responses.
J INTS BIO is also advancing plans to commercialize JIN-001 through partnerships with global pharmaceutical companies, aiming to bring faster and more effective treatments to brain tumor patients. Furthermore, the potential applications of JIN-001 are being explored in treating a wide range of cancers beyond brain tumors, providing new hope for cancer patients worldwide.
JIN-001 represents a groundbreaking innovation that transcends the limitations of existing therapies, offering new treatment opportunities and hope for improved survival and quality of life for brain tumor patients.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
J INTS BIO and MD Anderson Collaborate on the Development of Brain Tumor Treatment 'JIN-001' - Enhancing Radiation and Chemotherapy Efficacy
BAKU, Azerbaijan, Nov. 25, 2024 /PRNewswire/ -- The Government of Indonesia, represented by the Special Envoy of the President of the Republic of Indonesia, Hashim Djojohadikusumo, has attracted EUR 1.2 billion in green financing for the power sector from Kreditanstalt für Wiederaufbau (KfW). This agreement was finalized during the 29th Conference of the Parties (COP29) in Baku, Azerbaijan, on Wednesday (11/13). The funding will be allocated to the development of various green power infrastructures, supporting the nation's sustainable energy transition.
The partnership was formalized by the signing of a Memorandum of Understanding (MoU) between PT PLN (Persero) and KfW. This partnership focuses on developing clean energy projects, specifically Pumped Storage Hydropower Plants and transmission network to connect green power plants.
Hashim Djojohadikusumo emphasized that the government of Indonesia is committed to reducing carbon emissions through energy transition by fostering collaborations at the global level, the shift towards renewable energy is expected to support energy self-sufficiency and drive national economic growth. He affirmed, "We have developed a new strategy over the next five years to achieve a minimum of 8% sustainable economic growth."
He underscored that the development of clean energy sources is crucial for enhancing Indonesia's industrial competitiveness. Over the next 15 years, the country targets a 75 percent increase in renewable energy generation capacity, contributing to the planned addition of 100 gigawatts (GW) of electricity capacity. "As a major nation, we are committed to fulfilling our responsibility to protect the future of our environment. We deeply appreciate the established international cooperation, which is a testament of our collective efforts in achieving the Net Zero Emissions (NZE) target,"
Darmawan Prasodjo, President Director of PT PLN (Persero) ("PLN"), expressed the corporation's firm support towards the government's initiatives in advancing energy transition. Various collaborations and initiatives have been implemented by PLN to ensure the success of sustainable electricity projects.
He noted that KfW's involvement in PLN's green projects is expected to drive more international partners to collaborate, cultivating a synergy of sustainable strategic, technical, and investment collaboration to accelerate global climate action. "This collaboration signifies PLN's proactive steps in expanding international partnerships to enhance national energy self-sufficiency in line with global climate actions."
Jürgen Kern, Sustainability Officer of KfW Group, explained that KfW's support for Indonesia demonstrates Germany's commitment to international cooperation for green transformation. Furthermore, Jürgen highlighted that PLN is at the center of Indonesia's energy transition, underscoring the company's unwavering support to greening the energy sector, while maintaining reliable energy access.
"Therefore, we believe that Indonesia and Germany can continue to strengthen partnership in the energy sector, moreover, in clean energy projects, like renewable energy and transmission. Achieving the NZE target requires robust collaboration and partnership," he concluded.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
Special Envoy of Indonesia, Hashim Djojohadikusumo Attracts EUR 1.2 Billion of Green Financing in Electricity Sector at COP29
