A Perfect Harmony of Fashion, Technology, and K-Pop – 2024 Runway to Seoul Concludes with Great Success
- Dynamic runway shows from leading K-fashion brands including RAIVE, RE_RHEE, MINA CHUNG, Ordinary People, VALOREN, TRIPLEROOT, and DUCKDIVE.
- Global campaign for K-fashion live-streamed worldwide with renowned domestic and international influencers.
- Positioned as more than a fashion show – a global platform blending K-culture and cutting-edge technology.
SEOUL, South Korea, Jan. 8, 2025 /PRNewswire/ -- The 2024 Runway to Seoul, held at Dongdaemun Design Plaza (DDP), wrapped up amidst fervent enthusiasm. Now in its second year, the event celebrated a unique fusion of fashion, beauty, K-pop, and advanced technology, showcasing the global potential of K-culture. Over 2,500 attendees experienced the energy and possibilities of K-fashion.
A Stage of Innovation and Creativity for K-Fashion
Hosted at DDP, an iconic cultural landmark designed by world-renowned architect Zaha Hadid, the event brought together fashion, art, and technology in a futuristic setting. The 2024 Runway to Seoul delivered a creative platform like no other, seamlessly blending elements of culture and innovation.
Notable international influencers, including Australian powerhouse Eunice Wani, who boasts 15 million followers, and Mongolian influencer Dulguun Odkhuu, attended to amplify the global appeal of K-fashion. Beyond being spectators, they actively engaged with and shared the cultural fusion of K-fashion in real-time, connecting with audiences worldwide.
Unique and Creative Runway Highlights
This year's runway featured seven prominent K-fashion brands, each captivating the audience with their innovative styles and performances. Returning participants MINA CHUNG and Ordinary People were joined by newcomers DUCKDIVE, VALOREN, TRIPLEROOT, RE_RHEE, and RAIVE, all of whom brought their distinctive flair to the stage. RE_RHEE encapsulated the creative ethos of the Seongsu-dong fashion scene, while MINA CHUNG presented bold interpretations of abstract Eastern aesthetics. Ordinary People charmed the audience with its understated yet emotive styles, widely admired by celebrities, and VALOREN offered a fresh take on deconstructivism, redefining it for modern men's daily fashion.
DUCKDIVE opened the runway with its street-smart designs in collaboration with the I'AM dance crew. TRIPLEROOT, known for contemporary women's fashion, partnered with K-Tigers dance crew for a vibrant performance. RAIVE closed the show with its debut fashion showcase, blending free-spirited vintage aesthetics with hip-hop dance crew HolyBang for a boundary-breaking finale.
The 2024 Runway to Seoul ended on a high note with performances by 4th-generation girl group H1-KEY, dance crew WE DEM BOYZ, and DJ SURA, leaving audiences with unforgettable memories and cementing the event as a hallmark celebration of K-fashion and culture.
Exclusive Experiences and Collaborations
The 2024 Runway to Seoul also offered attendees the chance to engage directly with participating brands. Limited-edition collaborations with all seven brands were exclusively available through the platform KREAM, alongside RTS-branded merchandise, which sold out due to overwhelming demand.
Renowned brands such as NARS, a luxury New York cosmetics company, VILLA ERBATIUM, a Korean fragrance house, DAILYBEER, known for its craft beers, and photo booth brand MMT added to the vibrant atmosphere, providing unique and memorable experiences for influencers and attendees alike.
K-Fashion and K-Culture Shine on the Global Stage
Organized by the Seoul Business Agency (SBA) and WWD Korea, the event showcased the potential of K-fashion as a global platform integrating fashion, K-pop, and technology. Beyond a fashion show, it highlighted the diversity and depth of K-culture for an international audience.
Hyunwoo Kim, CEO of SBA, stated, "Runway to Seoul is a unique cultural festival born from the fusion of K-fashion, K-pop, and technology. It goes beyond being a fashion show, revealing the potential and creativity of K-fashion to the world, contributing to its strengthened presence in the global market."
A flagship program of SEOULCon, the global influencer expo organized by SBA, Runway to Seoul attracted over 3,500 influencer teams from more than 50 countries, firmly establishing itself as a major global cultural festival.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
Showcasing the Vibrant Lifestyle of Seoul: 2024 Runway to Seoul
Showcasing the Vibrant Lifestyle of Seoul: 2024 Runway to Seoul
Showcasing the Vibrant Lifestyle of Seoul: 2024 Runway to Seoul
Showcasing the Vibrant Lifestyle of Seoul: 2024 Runway to Seoul
BEIJING, Jan. 9, 2025 /PRNewswire/ -- In a recent achievement, DP Technology's hit discovery platform RiDYMO® has successfully designed a cyclic peptide targeting β-catenin, a historically "undruggable" protein, in just two months. This innovative AI-driven approach combines advanced algorithms, physics simulations, and high-throughput experimentation to rapidly develop potential drug candidates for challenging targets. The platform's success with β-catenin, a key player in cancer development, demonstrates its potential to revolutionize drug discovery for previously intractable targets.
The Wnt/β-catenin pathway plays a crucial role in various biological functions and is implicated in multiple cancers[1-3]. Despite its importance as a therapeutic target[4-7], β-catenin has long been considered "undruggable" due to its flat protein surface[8-10]. The RiDYMO® platform overcomes this challenge by leveraging a vast library of over 10^12 cyclic peptides and macrocyclic molecules, incorporating both natural and non-natural amino acids.
Using the RiDYMO® platform, researchers rapidly designed and screened cyclic peptide molecules for β-catenin binding. The process involved:
The results were impressive, with 12 compounds showing strong inhibition of protein-protein interactions (IC50≤10 μM), a success rate of over 40%. One standout compound, designated as compound 24, effectively bound to β-catenin, disrupted its interaction with BCL9, and inhibited the Wnt/β-catenin signaling pathway.
Dr. Dongdong Wang, Co-President of DP Technology's Drug Discovery Unit, emphasized the platform's ability to tackle undruggable targets and rapidly design high-quality compounds. The RiDYMO® platform's success with β-catenin demonstrates its potential to accelerate the development of orally available cyclic peptide drugs, potentially transforming the pharmaceutical industry's approach to challenging targets.
This breakthrough in cyclic peptide design for β-catenin showcases the power of AI-driven drug discovery platforms in addressing previously intractable targets, potentially opening new avenues for cancer treatment and other therapeutic areas.
About the RiDYMO® Hit Discovery and Optimization Platform
RiDYMO® is a state-of-the-art hit discovery and optimization platform developed by DP Technology, leveraging the principles of AI for Science. It employs the proprietary Hermite® computational drug design software to elucidate the dynamics of "undruggable" targets and explores a broader chemical space encompassing small molecules, macrocycles, and cyclic peptides. By integrating advanced artificial intelligence, physics-based algorithms, and high-throughput experimentation, the platform excels in designing oral macrocyclic compounds and rapidly delivers innovative drug candidates.
As one of its core algorithms, Reinforced Dynamics (RiD)[4] has a significant advantage in the sampling efficiency of molecular dynamics simulation. By fully leveraging the high-dimensional representation capabilities of neural networks, RiD can efficiently capture dynamic conformational changes in complicated biomolecular systems. Previously, the core RiD algorithm of the platform was published in Nature Computational Science [11]. The study demonstrated that RiD could achieve a more comprehensive free energy surface within 1.86 μs, compared to 100 μs required by traditional MD methods, representing nearly a hundredfold increase in efficiency.
RiDYMO® has been successfully employed in various drug discovery programs, including the development of small molecule compounds for crucial targets such as c-Myc and GPX4, as well as other modalities such as cyclic peptides and ADCs.
For more information, please visit our website.
(https://www.dp.tech/en/services/medicine).
About Hermite
Hermite® is a next-generation computational drug design platform developed by DP Technology, powered by AI for Science, to provide a comprehensive solution for drug design. Hermite® integrates industry-leading tools such as the Free Energy Perturbation module ("Uni-FEP"), and the ultra-high-throughput virtual screening tool ("Uni-VSW"). The platform supports key stages of drug discovery from protein structure prediction and target validation to hit discovery and lead optimization.
In addition, the platform offers an interactive, web-based molecular visualization experience, with detailed management of projects, teams, and data. It features full compliance certification, multi-tier security measures. Users have the flexibility to choose between cloud-based or private deployment options.
Hermite® is rapidly gaining traction in the pharmaceutical industry, with over 60% of leading companies in China utilizing the platform across more than 50 drug pipelines. This growing trust is reflected in the impressive number of calculations performed—over 200,000 Uni-FEP calculations to date—demonstrating Hermite®'s reliability and effectiveness as a powerful tool for drug discovery and development.
For more information, please visit: https://www.dp.tech/en/product/hermite
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** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
RiDYMO® Designs Cyclic Peptide for "Undruggable" β-Catenin Target Within Two Months
RiDYMO® Designs Cyclic Peptide for "Undruggable" β-Catenin Target Within Two Months
RiDYMO® Designs Cyclic Peptide for "Undruggable" β-Catenin Target Within Two Months
