YQN at CES 2025: Redefining Smart Logistics for Global Trade

LAS VEGAS, Jan. 9, 2025 /PRNewswire/ -- The globally renowned CES, widely recognized as a barometer of consumer electronics and technology trends, recently opened in Las Vegas, USA, attracting technology giants, business leaders, and media from around the world. As a leading digitalized international logistics provider, YQN showcased a series of technology-driven intelligent logistics solutions and integrated warehousing services at LVCC North Hall. By deeply integrating technologies such as Artificial Intelligence (AI), automation equipment, and Robotic Process Automation (RPA), YQN has successfully optimized key logistics industry challenges in efficiency and visibility management, delivering highly competitive logistics solutions for cross-border e-commerce and traditional trade clients.

YQN's robust technology infrastructure supports a comprehensive logistics network that spans first-mile transportation, warehousing, and last-mile delivery, addressing the complex and dynamic needs of cross-border logistics. Its proprietary smart logistics platform enables online pricing, booking, real-time order tracking, and full-process visibility, ensuring transparency and efficiency throughout the entire logistics journey.                                                          

On the digital front, YQN leverages RPA technology to streamline booking, document processing and workflow management. RPA robots can complete complex document entries within 30 seconds, significantly boosting efficiency and accuracy. Moreover, RPA enables seamless integration with client ERP systems, shipping companies, and supplier platforms, ensuring real-time data synchronization and greatly enhancing supply chain collaboration. These advanced technologies make logistics management more efficient and precise, delivering exceptional value to clients.

YQN has established over 14 strategically located warehouses across North America, including key cities such as Los Angeles, New Jersey, Savannah, Atlanta, Houston, and Mexico City, with a total storage area exceeding 3 million square feet. These facilities handle small to oversized goods efficiently, providing flexible solutions tailored to diverse client needs.

As a certified semi-managed warehouse partner for Temu and SheIn and a trusted logistics provider for Wayfair and Amazon, YQN meets Amazon's rigorous Seller Fulfilled Prime (SFP) standards, enabling clients to seamlessly access the PRIME market.

YQN enhances operational efficiency through its advanced Warehouse Management System (WMS) and automation equipment. By integrating WMS with AMR robots, AVG mobile robots, and RFID tags, YQN optimizes handling, sorting, inventory management, and distribution processes. In particular, the combination of three-way forklifts and AMR robots in narrow-aisle warehousing not only optimizes warehouse operations but also provides clients with more competitive services.  Additionally, YQN's intelligent BI reports can help clients reduce logistics costs by 10%-30% and shorten delivery times.

YQN serves warehouse clients across various industries, such as automotive & auto parts, new energy vehicles, digital products, smart home appliances & furniture, fitness equipment, and machinery tools.

YQN delivered a tailored, end-to-end relocation solution for a prominent consumer electronics brand in North America. The two-phase project involved transferring hundreds of containers from three warehouses to YQN's North American facilities. Leveraging its global network of 25 branches and advanced digital systems, YQN ensured seamless collaboration between domestic and international teams. The domestic team completed the relocation plan within just one week, while the local team efficiently executed sorting operations, minimizing disruptions to the client's daily sales and logistics activities.

Following the relocation, the client used YQN's digital platform to monitor inventory dynamics and multi-channel shipments in real time, significantly improving management efficiency and supply chain coordination. YQN's digital system integrates with major e-commerce platforms such as Amazon, Wayfair, Walmart, ensuring synchronized global operations. Partnerships last-mile delivery providers like FedEx and UPS optimized delivery costs and enhanced efficiency. In unexpected situations, YQN's teams coordinated swiftly across time zones, delivering professional, high-quality service that earned praise from the client.

To address the complex inventory management and distribution challenges of furniture clients, YQN established dedicated storage zones in its warehouses and optimized operational precision, significantly reducing product damage. YQN also provided proxy appointment services for both shipping and receiving warehouses, lowering communication costs and improving efficiency. Tailored fulfillment solutions, supported by dedicated account managers ensured issue resolution and smooth operations. As a result, furniture clients achieved 99% on-time delivery rates, enhancing both operational efficiency and customer satisfaction.

YQN's Co-founder& COO, Alice Xu stated, "YQN will continue advancing the digital and intelligent transformation of logistics, empowering clients to enhance operational efficiency through technological innovation. We are committed to building transparent and precise logistics management systems, injecting new energy into the global logistics industry."

This CES exhibition underscored YQN's practical approach to leveraging advanced technologies in addressing the challenges of international trade. It highlighted the company's commitment to fostering innovation, enhancing supply chain collaboration, and building adaptable logistics ecosystems. As global markets evolve, YQN remains focused on delivering reliable solutions that meet the demands of a dynamic and rapidly changing world.

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

YQN at CES 2025: Redefining Smart Logistics for Global Trade

BEIJING, Jan. 9, 2025 /PRNewswire/ -- In a recent achievement, DP Technology's hit discovery platform RiDYMO® has successfully designed a cyclic peptide targeting β-catenin, a historically "undruggable" protein, in just two months. This innovative AI-driven approach combines advanced algorithms, physics simulations, and high-throughput experimentation to rapidly develop potential drug candidates for challenging targets. The platform's success with β-catenin, a key player in cancer development, demonstrates its potential to revolutionize drug discovery for previously intractable targets.

The Wnt/β-catenin pathway plays a crucial role in various biological functions and is implicated in multiple cancers[1-3]. Despite its importance as a therapeutic target[4-7], β-catenin has long been considered "undruggable" due to its flat protein surface[8-10]. The RiDYMO® platform overcomes this challenge by leveraging a vast library of over 10^12 cyclic peptides and macrocyclic molecules, incorporating both natural and non-natural amino acids.

Using the RiDYMO® platform, researchers rapidly designed and screened cyclic peptide molecules for β-catenin binding. The process involved:

The results were impressive, with 12 compounds showing strong inhibition of protein-protein interactions (IC50≤10 μM), a success rate of over 40%. One standout compound, designated as compound 24, effectively bound to β-catenin, disrupted its interaction with BCL9, and inhibited the Wnt/β-catenin signaling pathway.

Dr. Dongdong Wang, Co-President of DP Technology's Drug Discovery Unit, emphasized the platform's ability to tackle undruggable targets and rapidly design high-quality compounds. The RiDYMO® platform's success with β-catenin demonstrates its potential to accelerate the development of orally available cyclic peptide drugs, potentially transforming the pharmaceutical industry's approach to challenging targets.

This breakthrough in cyclic peptide design for β-catenin showcases the power of AI-driven drug discovery platforms in addressing previously intractable targets, potentially opening new avenues for cancer treatment and other therapeutic areas.

About the RiDYMO® Hit Discovery and Optimization Platform

RiDYMO® is a state-of-the-art hit discovery and optimization platform developed by DP Technology, leveraging the principles of AI for Science. It employs the proprietary Hermite® computational drug design software to elucidate the dynamics of "undruggable" targets and explores a broader chemical space encompassing small molecules, macrocycles, and cyclic peptides. By integrating advanced artificial intelligence, physics-based algorithms, and high-throughput experimentation, the platform excels in designing oral macrocyclic compounds and rapidly delivers innovative drug candidates.

As one of its core algorithms, Reinforced Dynamics (RiD)[4] has a significant advantage in the sampling efficiency of molecular dynamics simulation. By fully leveraging the high-dimensional representation capabilities of neural networks, RiD can efficiently capture dynamic conformational changes in complicated biomolecular systems. Previously, the core RiD algorithm of the platform was published in Nature Computational Science [11]. The study demonstrated that RiD could achieve a more comprehensive free energy surface within 1.86 μs, compared to 100 μs required by traditional MD methods, representing nearly a hundredfold increase in efficiency.

RiDYMO® has been successfully employed in various drug discovery programs, including the development of small molecule compounds for crucial targets such as c-Myc and GPX4, as well as other modalities such as cyclic peptides and ADCs.

For more information, please visit our website.

(https://www.dp.tech/en/services/medicine).

About Hermite

Hermite® is a next-generation computational drug design platform developed by DP Technology, powered by AI for Science, to provide a comprehensive solution for drug design. Hermite® integrates industry-leading tools such as the Free Energy Perturbation module ("Uni-FEP"), and the ultra-high-throughput virtual screening tool ("Uni-VSW"). The platform supports key stages of drug discovery from protein structure prediction and target validation to hit discovery and lead optimization.

In addition, the platform offers an interactive, web-based molecular visualization experience, with detailed management of projects, teams, and data. It features full compliance certification, multi-tier security measures. Users have the flexibility to choose between cloud-based or private deployment options.

Hermite® is rapidly gaining traction in the pharmaceutical industry, with over 60% of leading companies in China utilizing the platform across more than 50 drug pipelines. This growing trust is reflected in the impressive number of calculations performed—over 200,000 Uni-FEP calculations to date—demonstrating Hermite®'s reliability and effectiveness as a powerful tool for drug discovery and development.

For more information, please visit: https://www.dp.tech/en/product/hermite  

References:

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

RiDYMO® Designs Cyclic Peptide for "Undruggable" β-Catenin Target Within Two Months

RiDYMO® Designs Cyclic Peptide for "Undruggable" β-Catenin Target Within Two Months

RiDYMO® Designs Cyclic Peptide for "Undruggable" β-Catenin Target Within Two Months