Waters Sets New Standards for High Resolution Performance and Speed with Xevo MRT Mass Spectrometer

News Summary:

ANAHEIM, Calif., and MILFORD, Mass., June 4, 2024 /PRNewswire/ -- 72^nd ASMS Conference on Mass Spectrometry and Allied Topics – Waters Corporation (NYSE: WAT) today unveiled the Xevoâ„¢ MRT, its highest-performing benchtop mass spectrometer (MS), setting new standards for delivering high resolution and speed, critical for large population and epidemiology-type studies. It builds on the innovative technology pioneered by the Waters SELECT SERIESâ„¢ MRT MS. The new Xevo MRT MS combines the raw power and resolution speed of multi-reflecting time-of-flight (MRT) and hybrid quadrupole time-of-flight (QTof) technologies within a flexible benchtop platform.

"Understanding complex diseases requires analysis of thousands of samples from large human cohorts to provide statistically valid studies. This puts increased pressure on drug discovery scientists to deliver high-quality data in shorter run times," said Dr. Udit Batra, CEO and President of Waters Corporation. "The Xevo MRT mass spectrometer is a next generation QTof built from the ground up to address this unmet need, delivering high resolution and speed without compromising analytical performance. Its multi-reflecting time-of-flight design enables simultaneous high sensitivity, high resolution, and speed in a small footprint, accelerating time-to-results and ensuring high-quality experimental outcomes."

The Xevo MRT system delivers a class-leadingⁱⁱⁱ 100,000 full width half maximum (FWHM) resolution at 100 Hz MS/MS scan speed and <500 parts per billion (ppb) mass accuracy. This enables deeper probing of biologically relevant concentrations with high levels of mass accuracy, independent of acquisition rate.

"A range of mass spec approaches are available for metabolomic, lipidomic, and metabolite identification studies, yet all require compromises to be made - either in data quality or analytical efficiency," said Professor Perdita Barran, Chair of Mass Spectroscopy in the University of Manchester (UK) Department of Chemistry and Director of the Michael Barber Centre for Collaborative Mass Spectrometry at the Manchester Institute of Biotechnology. "The Xevo MRT MS is impressive technology capable of higher sample throughput combined with extremely high precision, which can significantly advance target validation and phenotyping studies. The increase in scan speed and data quality are critical as it can allow us to run more samples in less time without compromising confidence in our data and we are very excited by how this is allowing us to accelerate the development of a diagnostic test for Parkinson's Disease."

The innovative multi-reflecting time-of-flight design of the Xevo MRT MS offers scientists the power to work at maximum resolution with high sensitivity and fast data acquisition rates. This helps ensure confident identification of analytes across a range of samples and complex matrices and generate comprehensive and highly accurate mass data for scientific interpretation.

Waters offers complete workflows for metabolomic, lipidomic, and metabolite identification for the Xevo MRT MS, alongside Waters high throughput ACQUITYâ„¢ UPLCâ„¢ Systems and UPLC Column chemistries and waters_connectâ„¢ Software for data acquisition, processing, and reporting. The system supports universal data-sharing via mzML file formats with third-party informatics software, including popular applications from Mass Analyticaâ„¢ such as its MARS, Lipostar2, and MassMetaSite software offerings.

The Waters Xevo MRT MS is orderable today for shipment in the second half of 2024.

Additional Resources

About Waters Corporation (www.waters.com)

Waters Corporation (NYSE: WAT), a global leader in analytical instruments and software, has pioneered chromatography, mass spectrometry, and thermal analysis innovations serving the life, materials, food, and environmental sciences for more than 65 years. With approximately 7,700 employees worldwide, Waters operates directly in 35 countries, including 15 manufacturing facilities, and with products available in more than 100 countries.

Waters, Xevo, SELECT SERIES, ACQUITY, UPLC, and waters_connect are trademarks of Waters Technologies Corporation. Mass Analytica is a trademark of Mass Spec Analytica, S.L.

Contact:
Janice Foley
Senior Public Relations Manager, Corporate Communications
Waters Corporation
janice_foley@waters.com
+1.617.823.5555

ⁱ Estimates based on Xevo MRT MS performance comparison to competitor instruments @100Hz @m/z 956 = 100K FWHM and <500ppb mass accuracy.
ⁱⁱ Xevo MRT MS Resolution of 100K FWHM @ m/z 956 is up to 1.5x to 6x competitor instruments @100Hz; Xevo MRT Mass Accuracy of <500ppb is 2x competitor systems @ 1ppm.
ⁱⁱⁱ Xevo MRT MS Resolution of 100K FWHM @ m/z 956 is up to 1.5x to 6x competitor instruments @100Hz; Xevo MRT Mass Accuracy of <500ppb is 2x competitor systems @ 1ppm.

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Waters Sets New Standards for High Resolution Performance and Speed with Xevo MRT Mass Spectrometer

HANGZHOU, China, April 2, 2025 /PRNewswire/ -- Hikvision announces the release of HikCentral Professional (HCP) v3.0, an advanced software platform for integrated security management. The new version introduces a powerful new clustering architecture designed to scale seamlessly with business growth. This delivers exceptional capacity and performance, making it ideal for large-scale applications in retail chains, multi-site banking networks, smart communities, and more.

Fred Wu, Product Director at Hikvision, emphasized the upgrade's significance: "The release of HCP v3.0 marks a transformative leap in security management. By integrating clustering architecture and load-balancing technologies, the new version empowers enterprises to future‑proof their operations while maintaining performance. This is more than an incremental upgrade—it introduces a new strategic tool for enterprises that need to thrive in dynamic environments."

Scalable clustering architecture: built for growth

Many system administrators know that a single server can struggle under the system processing loads demanded by large projects. In previous versions, a single server could support up to 10,000 video channels, but with HCP v3.0, this capacity has been doubled to 20,000 video channels per server. However, for enterprises with even greater demands, HCP v3.0 introduces a robust and flexible clustering architecture that allows businesses to expand server resources on demand. Key features include:

A single master server can be dynamically scaled to 5 slave servers, supporting up to 55,000 devices and 50,000 video channels—ideal for enterprises managing vast security networks.

The new architecture ensures uninterrupted operations even during server failures with the introduction of hot standby master and slave servers. This failover capability is constantly powered on and continuously synchronized with the master server, ready to take over immediately. Users can customize the number of standby servers based on budget and risk tolerance.

Elevated streaming performance

As video processing demands grow, HCP v3.0 delivers unparalleled efficiency. The ability to support external streaming media has been optimized. Moreover, HCP v3.0 now supports the streaming server cluster powered by load-balancing technologies. These dynamically allocate new requests to the least loaded servers, optimizing resource use and guaranteeing smooth video retrieval even during peak usage.

Enterprise-grade data management and security

HCP v3.0 addresses escalating data needs with robust storage and redundancy. The external PostgreSQL database supports billions of records for rapid storage and retrieval. This is particularly beneficial for applications including on-board security, access control, portable enforcement, and more, each of which can store up to 1 billion records. Meanwhile, the hot backups safeguard against storage failures, ensuring zero data loss.

Unified visual management

HCP v3.0 gives administrators complete control through an intuitive interface which visually represents the configured architecture. Users can quickly add, remove, or modify servers by dragging and dropping. Dynamic dashboards enable real-time monitoring of server health and data migration status.

Explore HikCentral Professional v3.0's full capabilities here, and stay tuned for more advancements as we continue to expand the boundaries of integrated security solutions.

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Hikvision launches HikCentral Professional v3.0 with an upgraded clustering architecture