FREMONT, Calif., Nov. 19, 2024 /PRNewswire/ -- Alamar Biosciences, a company powering precision proteomics to enable the earliest detection of disease, is pleased to announce a strategic collaboration with The Michael J. Fox Foundation for Parkinson's Research (MJFF) to accelerate biomarker discovery and improve our understanding of Parkinson's disease (PD). This collaboration aims to address the critical need for robust biological classification of PD and related neurodegenerative diseases. By leveraging Alamar's advanced proteomics platform, the team will develop novel protein assays tailored to identifying key biomarkers associated with neuronal synuclein disease.
In addition to partnering on efforts to expand the analytes in the NULISAseqâ„¢ CNS Disease Panel 120 to include additional PD-relevant targets, MJFF will also deploy the high-sensitivity NULISAseqâ„¢ CNS Disease Panel 120 and Inflammation Panel 250 to analyze roughly 5,000 samples from MJFF's flagship longitudinal study, the Parkinson's Progression Markers Initiative (PPMI). Launched in 2010, PPMI has built the most robust dataset and biosample library ever assembled in Parkinson's research.
"We are honored to join forces with The Michael J. Fox Foundation, a true leader in driving research toward a cure for Parkinson's disease," said Yuling Luo, Founder, Chairman & CEO of Alamar Biosciences. "The comprehensive analysis of the PPMI cohort using our NULISAseqâ„¢ technology provides a unique opportunity to uncover new insights into disease mechanisms and accelerate the development of targeted therapies."
The NULISASeqâ„¢ CNS Disease Panel 120 and Inflammation Panel 250 represent Alamar Bio's innovative approach to precision proteomics, enabling highly sensitive and multiplexed protein detection. By applying these panels to PPMI samples, the collaboration seeks to identify novel biomarkers that can improve early diagnosis, track disease progression, and aid in the development of next-generation treatments.
"Core to our mission, MJFF is committed to advancing research that addresses the critical, unmet needs of patients," said Nicole K. Polinski, PhD, Director of Research Resources at MJFF. "MJFF's collaboration with Alamar Biosciences aims to not only deepen our understanding of Parkinson's pathology but to support the development of urgently needed diagnostic and therapeutic tools."
The Michael J. Fox Foundation's landmark PPMI study, now in its second decade, has collected extensive clinical, imaging, and biosample data from PD patients, at-risk individuals, and healthy controls. These efforts have already paved the way for breakthroughs in understanding the underlying biology of PD, and the collaboration with Alamar Biosciences is expected to further accelerate progress.
By working together, Alamar Biosciences and The Michael J. Fox Foundation hope to make significant strides in addressing the unmet needs of the Parkinson's community, particularly in advancing biological classifications for neuronal synuclein disease.
About Alamar Biosciences, Inc.
Alamar Biosciences is a privately held life sciences company with a mission to power precision proteomics to enable the earliest detection of disease. The company's proprietary NULISA Platform along with the ARGOâ„¢ HT System work seamlessly with the latest advances in genomics to achieve single digit attomolar detection sensitivity, greatly surpassing the most sensitive protein detection technology on the market today. For more information, please visit alamarbio.com.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
Alamar Biosciences Announces Collaboration with The Michael J. Fox Foundation to Advance Parkinson's Research Through Development of Next Generation Biomarker Assays
SHENZHEN, China, Nov. 19, 2024 /PRNewswire/ -- X Foundation has announced a significant partnership with the Dream Building Service Association (DBSA), signing a plan to embark on a project to enhance the infrastructure of educational institutions, providing African children with more stable and improved access to education. The initiative is expected to contribute to sustained economic growth, technological innovation, and comprehensive social progress in the region.
DBSA is a non-profit organization that focuses on the survival and development of children in impoverished areas worldwide through education, social research, and community support. Annually, DBSA recruits volunteers to assist with education and the construction of schools in Mathare, Nairobi's second-largest slum, home to 600,000 people in less than three square kilometers. Despite problems with overcrowding, residents see education as a key to escaping poverty. However, since mid-March 2024, severe rains and floods in Kenya have destroyed many schools in Mathare, severely impacting educational facilities.
As part of the reconstruction plan, X Foundation will fund the rebuilding of three schools, concentrating on the design and enhancement of key educational facilities such as classrooms and libraries. The construction will utilize durable reinforced concrete to ensure structural integrity and safety. Additionally, the schools will feature quality finishes that not only provide aesthetic value but also contribute to a conducive learning environment.
In collaboration with international charitable organizations like DBSA, X Foundation is committed to advancing basic education for children in underprivileged areas of Kenya. The foundation seeks to replicate and promote the successful outcomes of its public welfare campus projects in China. Since 2023, X Foundation has partnered with the Education Technology and Sports Bureau of Xunwu County in China's Jiangxi Province, to support rural schools by building libraries, fostering a conducive reading environment, enhancing teachers' reading guidance skills, and organizing reading activities. This initiative has provided rural children with access to quality reading resources, effective reading methods, and the cultivation of good reading habits, making reading a fundamental aspect of rural education.
During this process, Keyu Ji, a student from the Shenzhen Senior High School Group International Division (SID), participated as a volunteer in the library project. Ji was involved in collecting ideas, sketching initial designs, and actively participating in the construction of the library, which was inspired by her design and officially opened in April 2024.
In her quest for design inspiration, Ji studied numerous design cases, drawing significant influence from the architectural philosophy and practice of Diébédo Francis Kéré, the 2022 Pritzker Architecture Prize laureate.
"Kéré once said 'Good architecture in Burkina Faso is a classroom where you can sit, have light that is filtered, entering the way that you want to use it, across a blackboard or on a desk.' His work, rooted in and serving the community, demonstrated architecture's mission to meet the actual needs of local people." Ji expressed her belief inspired by Kéré that architecture is not merely an aesthetic concept but exists for humanity.
As an architecture student, Ji has realized through her volunteer work that design can significantly enhance people's lives. She intends to continue contributing her design expertise to the African project as a volunteer with X Foundation. "I am excited to collaborate with everyone to promote educational public welfare in Africa while respecting nature and celebrating life sustainably," Ji said.
With support from young and talented volunteers like Ji, the X Foundation aims to explore a sustainable and replicable effective public welfare model through its practices in China and Kenya. The foundation aims to connect with more socially responsible entities, taking on social responsibility and creating sustainable social value.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
X Foundation Partners with Dream Building Service Association to Rebuild Schools in Kenya's Mathare Slum
