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Bruker Announces Successful Installation of 1.2 GHz Avance® NMR Spectrometer at the Korea Basic Science Institute (KBSI)

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Bruker Announces Successful Installation of 1.2 GHz Avance® NMR Spectrometer at the Korea Basic Science Institute (KBSI)
News

News

Bruker Announces Successful Installation of 1.2 GHz Avance® NMR Spectrometer at the Korea Basic Science Institute (KBSI)

2024-08-14 01:35 Last Updated At:01:41

SEOUL, South Korea--(BUSINESS WIRE)--Aug 13, 2024--

Bruker Corporation is pleased to announce the successful installation and acceptance of a 1.2 GHz Avance® Nuclear Magnetic Resonance (NMR) spectrometer at the Korea Basic Science Institute ( KBSI ), just in time before the start of the ICMRBS 2024 conference in Korea. As the first 1.2 GHz NMR system in the Asia-Pacific region, it sets a new benchmark for molecular, cell biology and disease research by ultra-high field NMR.

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This underscores KBSI’s unwavering commitment to innovation in research infrastructure, cementing its status as a world-class fundamental research institute. This cutting-edge 1.2 GHz NMR spectrometer further enhances KBSI’s capabilities in biomolecular structure analysis and drug development, pushing the boundaries of protein NMR research. Ultra-high field NMR provides excellent sensitivity and unprecedented resolution, enabling researchers to observe functional molecular dynamics and structural rearrangements in real time. Complementary to other structural biology technologies, GHz-class NMR allows KBSI to elucidate complex biological processes, such as protein-ligand interactions and the behavior of intrinsically disordered proteins, which are crucial for understanding disease mechanisms and developing new therapeutic strategies.

Dr. Hae-Kap Cheong, Manager of the UHF NMR system at KBSI, expressed his enthusiasm: “When using the 1.2 GHz instrument, the opportunities for small molecule research made me speechless. In particular, the structural elucidation of natural products will be greatly beneficial.”

Dr. Donghan Lee, Scientific Researcher at KBSI, adds: “As Richard Feynman said, ‘Everything that living things do can be understood in terms of the jiggling and wiggling of atoms.’ The function of biomolecules can be understood by their dynamic nature. In particular, the functional conformation of biomolecules may be hidden because of their dynamic nature. With the 1.2 GHz instrument, the detection of these conformations enables the unprecedented identification of functional conformations.”

KBSI is dedicated to advancing scientific research through state-of-the-art technology and innovative research facilities. As a platform for global basic research, KBSI connects research facilities, equipment, and researchers, driving the future of science and technology in the Asia-Pacific region. With its mission to lead the innovation of research facilities and equipment, KBSI continues to support advanced analytical research and joint research initiatives in Korea and beyond.

Dr. Kyoung-Seok Ryu, Director of the Biopharmaceutical Research Center at KBSI, added: “The application of the 1.2 GHz instrument includes mechanistic understanding, in particular, the mode-of-action of drug-target binding and molecular communication. Furthermore, studying intrinsically disordered or partially disordered proteins with the 1.2 GHz NMR instrument can elucidate the functional mechanisms underlying neurodegeneration.”

KBSI will utilize the 1.2 GHz spectrometer for a diverse range of research applications, including the study of biomolecular structures and the development of new drugs. This ultra-high field NMR instrument will support other KBSI research in biomedical multiomics, bioimaging, and the development of diagnostic methods for infectious diseases. The broader benefits of this research will extend to advancements in medical research, materials science, and other critical fields.

Dr. Falko Busse, President of Bruker BioSpin, commented: “We are thrilled to see the 1.2 GHz NMR become a key part of KBSI’s research infrastructure. Grateful for the trust from KBSI, we look forward to the scientific advancements that will emerge. We are pleased to offer a tour of the 1.2 GHz NMR at KBSI during the International Conference on Magnetic Resonance in Biological Systems.”

Interested researchers can book the tour at Bruker Booth A1 at ICMRBS for Friday, August 23, providing a unique opportunity to explore the advanced capabilities of this revolutionary instrument.

With the installation at KBSI, there are now 22 GHz-class NMR spectrometers installed worldwide, including two in the Asia-Pacific region. This demonstrates the growing recognition of the value GHz-class NMR brings to scientific research. Together with the first single-story 1.0 GHz NMR already installed in Japan, KBSI’s 1.2 GHz highlights the need for cutting-edge research infrastructure.

About Bruker Corporation – Leader of the Post-Genomic Era (Nasdaq: BRKR)

Bruker is enabling scientists and engineers to make breakthrough post-genomic discoveries and develop new applications that improve the quality of human life. Bruker’s high performance scientific instruments and high value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular, and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity, and customer success in post-genomic life science molecular and cell biology research, in applied and biopharma applications, in microscopy and nanoanalysis, as well as in industrial and cleantech research, and next-gen semiconductor metrology in support of AI. Bruker offers differentiated, high-value life science and diagnostics systems and solutions in preclinical imaging, clinical phenomics research, proteomics and multiomics, spatial and single-cell biology, functional structural and condensate biology, as well as in clinical microbiology and molecular diagnostics. For more information, please visit www.bruker.com.

Dr. Kyoung-Seok Ryu, Director of Biopharmaceutical Research Center, KBSI

Dr. Kyoung-Seok Ryu, Director of Biopharmaceutical Research Center, KBSI

1.2 GHz Avance® NMR system at Korea Basic Science Institute (KBSI)

1.2 GHz Avance® NMR system at Korea Basic Science Institute (KBSI)

Donald Trump began his first day as the 47th president of the United States with a dizzying display of force, signing a blizzard of executive orders that signaled his desire to remake American institutions while also pardoning nearly all of his supporters who rioted at the U.S. Capitol on Jan. 6, 2021.

Here's the latest:

U.S. Rep. Elise Stefanik of New York will be grilled about her lack of foreign policy experience at 10 a.m. ET and strong support for Israel as she vies to become U.S. ambassador to the United Nations.

Trump’s pick to lead the Veterans Affairs Department, former Georgia Rep. Doug Collins, is also up at 10 a.m. ET. He’s a chaplain in the U.S. Air Force Reserve Command who helped defend Trump during his first impeachment process.

A Senate committee will vote on money manager Scott Bessent, Trump’s choice for Treasury Secretary, at 10:15 ET. He’s an advocate of cutting spending while extending the tax cuts.

Speaking to Fox News, press secretary Karoline Leavitt declined to detail the announcement before Trump spoke at 4 p.m. Tuesday but said it would also send a signal to the world.

“You won’t want to miss it,” she said. Trump is also scheduled to attend a national prayer service Tuesday morning at Washington National Cathedral.

House Speaker Mike Johnson and Senate Majority Leader John Thune are heading to the White House to meet with Trump on Tuesday.

It’s the first formal sit down for the GOP leadership teams including Majority Leader Steve Scalise and Senate GOP Whip John Barrasso and the new president as they chart priorities with the sweep of Republican power in Washington.

Despite an ambitious 100-days agenda, the Republican-led Congress isn’t on the same page on some of the basics of their ideas and strategies as they rush to deliver tax cuts for the wealthy, mass deportations and other priorities for Trump.

He pledged to remove more than 1,000 presidential appointees “who are not aligned with our vision.”

In a post on his TruthSocial platform, Trump dismissed chef and humanitarian Jose Andres from the President’s Council on Sports, Fitness and Nutrition, Ret. Gen. Mark Milley from the National Infrastructure Advisory Council, former State Dept. official Brian Hook from the board of the Wilson Center, and former Atlanta Mayor Keisha Lance Bottoms from the President’s Export Council.

“YOUR’E FIRED!” he wrote in a post just after midnight Tuesday.

Milley, the former chairman of the joint chiefs of staff under Trump, received a pardon from former President Joe Biden on Monday over concerns he could be criminally targeted by the new administration. His portrait in the Pentagon was also removed. Hook, who was Trump’s Iran envoy during his first term, had been involved in the Trump administration transition. No reasoning was given for his firing.

Former President Joe Biden also removed many Trump appointees in his first days in office, including former press secretary Sean Spicer from the board overseeing the U.S. Naval Acadamy.

Rep. Elise Stefanik is likely to face questions at her confirmation hearing Tuesday to become the U.S. ambassador to the United Nations about her lack of foreign policy experience, her strong support for Israel and her views on funding the U.N. and its many agencies.

Harvard-educated and the fourth-ranking member of the U.S. House, she was elected to Congress in 2015 as a moderate Republican and is leaving a decade later as one of President Trump’s most ardent allies.

U.N. Secretary-General Antonio Guterres “looks forward to working again with President Trump on his second term,” U.N. deputy spokesman Farhan Haq said Monday.

When she appears before the Senate Foreign Relations Committee, Stefanik is likely to be grilled about her views on the wars in Gaza, Ukraine, Sudan and elsewhere as well as the North Korean and Iranian nuclear programs — all issues on the U.N. agenda.

▶ Read more about Elise Stefanik’s confirmation hearing

Scholz said at the World Economic Forum in Davos on Tuesday that “not every press conference in Washington, not every tweet should send us straight into excited, existential debates. That’s also the case after the change of government that took place in Washington yesterday.”

Scholz said the U.S. is Germany’s closest ally outside Europe and he’ll do everything to keep in that way.

He acknowledged that Trump and his administration “will keep the world on tenterhooks in the coming years” in energy, climate, trade and security policy. But he said “we can and will deal with all this, without unnecessary agitation and outrage, but also without false ingratiation or telling people what they want to hear.”

Scholz said of Trump’s “America First” approach that there’s nothing wrong with looking to the interests of one’s own country – “we all do that. But it is also the case that cooperation and agreement with others are mostly also in one’s interest.”

Speaking in the Oval Office Monday, Trump rejected Biden’s warning that the U.S. is becoming an “ oligarchy ” for tech billionaires, saying the executives supported Democrats until they realized Biden “didn’t know what the hell he was talking about.”

“They did desert him,” Trump added. “They were all with him, every one of them, and now they are all with me.”

Despite taking millions from the executives and their companies for his inaugural committee — and receiving more than $200 million in assistance from Musk in his presidential campaign — Trump claimed he didn’t need their money and they wouldn’t be receiving anything in return.

“They’re not going to get anything from me,” Trump said. “I don’t need money, but I do want the nation to do well, and they’re smart people and they create a lot of jobs.”

Some of the most exclusive seats at Trump’s inauguration on Monday were reserved for powerful tech CEOs who also happen to be among the world’s richest men.

That’s a shift from tradition, especially for a president who has characterized himself as a champion of the working class. Seats so close to the president are usually reserved for the president’s family, past presidents and other honored guests.

The mega-rich have long had a prominent role in national politics, and several billionaires helped bankroll the campaign of Trump’s Democratic opponent, Vice President Kamala Harris.

But the inaugural display highlights the unusually direct role the world’s wealthiest people will likely have in the new administration. In his outgoing address, Biden warned that the U.S. was becoming an oligarchy of tech billionaires wielding dangerous levels of power and influence on the nation.

▶ Read more about the billionaires at Trump’s inauguration

Outside the National Cathedral, just a few hours before the Interfaith Service of Prayer for the Nation, which both President Trump and Vice President JD Vance are expected to attend, the scene before was decidedly quiet.

At the Cathedral only a few dog walkers dotted the sidewalk and the police presence was low.

It was a far cry from yesterday when thousands lined up in downtown D.C. festooned in the red regalia of MAGA nation — or the security and foot traffic from earlier this month for the funeral service of former President Jimmy Carter where Secret Service vehicles could be seen at least a mile from the Cathedral.

The Senate quickly confirmed Marco Rubio as secretary of state Monday, voting unanimously to give Trump the first member of his new Cabinet on Inauguration Day.

Rubio, the Republican senator from Florida, is among the least controversial of Trump’s nominees and vote was decisive, 99-0.

It’s often tradition for the Senate to convene immediately after the ceremonial pomp of the inauguration to begin putting the new president’s team in place, particularly the national security officials.

▶ Read more about Marco Rubio’s confirmation

All the living former presidents were there and the outgoing president amicably greeted his successor, who gave a speech about the country’s bright future and who left to the blare of a brass band.

At first glance, President Donald Trump’ssecond inauguration seemed like a continuation of the country’s nearly 250-year-long tradition of peaceful transfers of power, essential to its democracy. And there was much to celebrate: Trump won a free and fair election last fall, and his supporters hope he will be able to fix problems at the border, end the war in Ukraine and get inflation under control.

Still, on Monday, the warning signs were clear.

Due to frigid temperatures, Trump’s swearing-in was held in the Capitol Rotunda, where rioters seeking to keep him in power the last time roamed during the Jan. 6, 2021, attack. Trump walked into the space from the hall leading to the building’s west front tunnel, where some of the worst hand-to-hand combat between Trump supporters and police occurred that day.

After giving a speech pledging that “never again” would the government “persecute political opponents,” Trump then gave a second, impromptu address to a crowd of supporters. The president lamented that his inaugural address had been sanitized, said he would shortly pardon the Jan. 6 rioters and fumed at last-minute preemptive pardons issued by outgoing President Joe Biden to the members of the congressional committee that investigated the attack.

▶ Read more about Trump’s Inauguration Day

President Donald Trump signs an executive order to create the Department of Government Efficiency (DOGE) in the Oval Office of the White House, Monday, Jan. 20, 2025, in Washington, as White House staff secretary Will Scharf watches. (AP Photo/Evan Vucci)

President Donald Trump signs an executive order to create the Department of Government Efficiency (DOGE) in the Oval Office of the White House, Monday, Jan. 20, 2025, in Washington, as White House staff secretary Will Scharf watches. (AP Photo/Evan Vucci)

President Donald Trump speaks as first lady Melania Trump listens at the Commander in Chief Ball, Monday, Jan. 20, 2025, in Washington. (AP Photo/Alex Brandon)

President Donald Trump speaks as first lady Melania Trump listens at the Commander in Chief Ball, Monday, Jan. 20, 2025, in Washington. (AP Photo/Alex Brandon)

President Donald Trump signs an executive order on TikTok in the Oval Office of the White House, Monday, Jan. 20, 2025, in Washington. (AP Photo/Evan Vucci)

President Donald Trump signs an executive order on TikTok in the Oval Office of the White House, Monday, Jan. 20, 2025, in Washington. (AP Photo/Evan Vucci)

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