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Lunit to Present AI-Analyzed Immune Phenotype Study as Immunotherapy Response Predictor for Advanced Gastric Cancer at ESMO Congress 2024

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Lunit to Present AI-Analyzed Immune Phenotype Study as Immunotherapy Response Predictor for Advanced Gastric Cancer at ESMO Congress 2024
Business

Business

Lunit to Present AI-Analyzed Immune Phenotype Study as Immunotherapy Response Predictor for Advanced Gastric Cancer at ESMO Congress 2024

2024-09-10 21:00 Last Updated At:21:15

SEOUL, South Korea, Sept. 10, 2024 /PRNewswire/ -- Lunit (KRX:328130.KQ), a leading provider of AI-powered solutions for cancer diagnostics and therapeutics, today announced the presentation of a significant study at the European Society for Medical Oncology (ESMO) Congress 2024 in Barcelona, Spain, from September 13-17.

While Nivolumab plus chemotherapy has recently been approved as a standard first-line treatment for advanced gastric cancer (AGC), its efficacy varies among patients. This variability underscores the critical need for reliable biomarkers to predict treatment response. Lunit's study addresses this pressing need, potentially offering a new tool to optimize patient care and treatment decisions.

Conducted in collaboration with leading Korean medical institutions, the research showcases the potential of Lunit's AI-powered histopathology analyzer, Lunit SCOPE IO®, in predicting treatment response and guiding treatment decisions for AGC via assessment of immune phenotype.

The study analyzed H&E images from 585 AGC patients, with Lunit SCOPE IO® classifying tumors into two immune phenotypes—inflamed (IIP) and non-inflamed—based on the presence and distribution of tumor-infiltrating lymphocytes (TILs) from hematoxylin and eosin (H&E) slides that are readily available from a standard clinical workup. This classification provided valuable insights into the tumor microenvironment and helped predict treatment response, particularly in cases where traditional biomarkers like PD-L1 may not provide a complete picture.

Key findings include:

1. Patients treated with Nivolumab+Chemotherapy showed significantly longer median progression-free survival (mPFS) compared to Chemotherapy alone (8.2 vs. 5.9 months).
2. The inflamed immune phenotype group, classified by Lunit SCOPE IO®, was associated with more pronounced PFS benefits from Nivolumab+Chemotherapy:

3. The predictive value of IIP was consistent across different PD-L1 expression levels.
4. Multivariate analysis confirmed IIP as an independent factor for PFS in patients treated with Nivolumab+Chemotherapy.

"By demonstrating that our AI-powered immune phenotype analysis can predict treatment response independently of PD-L1 status, we're opening new possibilities for tailoring treatments in AGC," said Brandon Suh, CEO of Lunit. "This is particularly significant because gastric cancer continues to be a leading cause of cancer-related deaths globally, representing 7.7% of all cancer cases. Our AI technology has the potential to enhance the precision of treatment decisions, potentially leading to more effective therapies and better quality of life for patients with AGC."

Please visit Lunit's poster session at 1411P to discover more about our findings and the innovative capabilities of Lunit SCOPE IO®.

Poster presentation featuring Lunit SCOPE IO at ESMO Congress 2024:

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About Lunit

Founded in 2013, Lunit (KRX:328130.KQ) is a medical AI company on a mission to conquer cancer. We harness AI-powered medical image analytics and AI biomarkers to ensure accurate diagnosis and optimal treatment for each cancer patient. Our FDA-cleared Lunit INSIGHT suite for cancer screening serves over 3,500 hospitals and medical institutions across 50+ countries.

Our clinical studies have been published in top journals, including the Journal of Clinical Oncology and the Lancet Digital Health, and presented at global conferences such as the ASCO and RSNA. In 2024, Lunit acquired Volpara Health Technologies, setting the stage for unparalleled synergy and accuracy, particularly in breast health and screening technologies. Headquartered in Seoul, South Korea, with a network of offices worldwide, Lunit leads the global fight against cancer. Discover more at lunit.io.

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Lunit to Present AI-Analyzed Immune Phenotype Study as Immunotherapy Response Predictor for Advanced Gastric Cancer at ESMO Congress 2024

Lunit to Present AI-Analyzed Immune Phenotype Study as Immunotherapy Response Predictor for Advanced Gastric Cancer at ESMO Congress 2024

SINGAPORE, Sept. 17, 2024 /PRNewswire/ -- The Asia Pacific Enterprise Awards (APEA) 2024 proudly celebrated Taiwan's leading business leaders and enterprises driving the future of inclusive entrepreneurship. In an exclusive ceremony held on 13th September at the Grand Hyatt, Taipei, industry leaders were honored for their outstanding contributions to fostering diverse, equitable, and innovative business practices. Organized by regional NGO Enterprise Asia, the APEA is Asia's largest award networking platform, spanning 16 markets annually. Under the theme "Celebrating Inclusive Entrepreneurship", the 2024 Awards recognize visionary business leaders whose initiatives and strategies have actively contributed to the realization of an inclusive entrepreneurship ecosystem in Taiwan.

The award recipients were selected from over 150 nominees through a rigorous evaluation process by a jury of prominent judges across four categories: Master Entrepreneur, Inspirational Brand, Fast Enterprise, and Corporate Excellence.

Since 2007, the Awards has been organized all over the region with past recipients comprising Taiwan's Douglas Tong Hsu, Hong Kong's Francis Lui and Lawrence Ho, TTC Vietnam's Dang Van Thanh, Thailand's Supaluck Ampuj, Cuckoo Malaysia's Hoe Kian Choon, Indonesia's Hary Tanoesoedibjo and Mochtar Riady, India's Adi Godrej, and the Philippines' Dennis Anthony Uy.

Dr. Fong Chan Onn, Chairman of Enterprise Asia, expressed in his welcome speech that "We stand at a pivotal moment where the entrepreneurial spirit can act as a powerful catalyst for change. By championing inclusive entrepreneurship, we can address social inequalities, create jobs, and foster resilient communities. Our collective efforts can lead to a future where entrepreneurship is not just a privilege for the few, but an opportunity for many."

Among the notable awardees are Fwusow Industry Co., Ltd.'s Chairman Yau-Kuen Hung, Excellence Optoelectronics Inc.'s President Huang, Fang-Yue, and Qisda Corporation's President Joe Huang, who have demonstrated exceptional commitment to fostering diversity and equal opportunities within the entrepreneurial landscape through championing inclusivity and creating pathways for various individuals to thrive in the business world.

Further outstanding awardees include Golden Insurance Brokers Co., Ltd. under the Fast Enterprise category, CPC Corporation, Taiwan and Wincomm Corporation under the Inspirational Brand category, and Pacific SOGO Department Stores Co., Ltd. and Raydium Semiconductor Corporation under the Corporate Excellence category.

The Asia Pacific Enterprise Awards 2024 Taiwan Chapter is supported by the Strategic Public Relations Group (SPRG) and Taiwan Institute for Sustainable Energy (TAISE), with KPMG Taiwan as the Official Assurance Partner. PR Newswire is the Official News Release Distribution Partner, and Commercial Times, Dailywire.asia, and SME Magazine are the Media Partners.

AWARD RECIPIENT LIST OF THE ASIA PACIFIC ENTERPRISE AWARDS 2024 TAIWAN CHAPTER

MASTER ENTREPRENEUR CATEGORY

NAME

COMPANY

INDUSTRY

LAI WEN CHANG

 

CHAIRMAN

ALLJACK TECHNOLOGIES, INC.

MANUFACTURING

LAI HUNG

 

FOUNDER & CHAIRMAN

ARTISTIC BIOMEDICAL LIMITED COMPANY

HEALTHCARE, PHARMACEUTICAL & BIOTECHNOLOGY

LINDA LU

 

CHAIRMAN

AWESOME GROUP

EDUCATION & TRAINING

KAI-LUN HUANG

 

CHAIRMAN & CEO

BAUSEN INC.

BUILDING MATERIALS

HUANG, SHIH-CHUN

 

CHAIRMAN

CHAINSEA INFORMATION INTEGRATION CO., LTD.

TELECOMMUNICATIONS & ICT

LEE SHUN-CHIN

 

CHAIRMAN & STANDING DIRECTOR

CPC CORPORATION, TAIWAN

OIL & GAS

ANDY SU

 

CHAIRMAN & CEO

DARFON ELECTRONICS CORP.

MANUFACTURING

HUANG, FANG-YUE

 

PRESIDENT

EXCELLENCE OPTOELECTRONICS INC.

AUTOMOTIVE

DR. YUNG-CHANG CHANG

 

MANAGING DIRECTOR

FAR EASTERN ELECTRONIC TOLL COLLECTION CO., LTD.

TRANSPORTATION & LOGISTICS

RICK LIAO

 

CHAIRMAN

FORESTAR BROKERAGE CO., LTD.

FINANCIAL SERVICES

YAU-KUEN HUNG

 

CHAIRMAN

FWUSOW INDUSTRY CO., LTD.

FOOD & BEVERAGE

CHANG, CHIH-CHIANG

 

CEO

GLORY TECHNOLOGY SERVICE INC.

TELECOMMUNICATIONS & ICT

WILLIAM TSAI

 

GENERAL MANAGER

GOLDEN INSURANCE BROKERS CO., LTD.

FINANCIAL SERVICES

EDWARD HSIEH

 

CHAIRMAN

HD RENEWABLE ENERGY CO., LTD

ENERGY

CHEN, YING-CHIH

 

CEO

HUSHAN AUTOPARTS INC.

AUTOMOTIVE

WAYNE YANG

 

GENERAL MANAGER

IV TECHNOLOGIES CO., LTD.

MANUFACTURING

CHENG, CHENG-KUN

 

PRESIDENT

NAN HOANG TRAFFIC INSTRUMENT CO., LTD.

MANUFACTURING

SHU-CHEN CHEN

 

GENERAL MANAGER

NEFFUL INTERNATIONAL HOLDINGS PTE. LTD., TAIWAN BRANCH

DIRECT SELLING

JOE HUANG

 

PRESIDENT

QISDA CORPORATION

MANUFACTURING

HERMIT YK HUANG

 

CHAIRMAN & CEO

RAYDIUM SEMICONDUCTOR CORPORATION

SEMICONDUCTOR

CHENG HSIEN WU

 

CHAIRMAN

YUAN JIN CHUANG ENTERPRISE CO., LTD.

FOOD & BEVERAGE

FAST ENTERPRISE CATEGORY

COMPANY

INDUSTRY

FORESTAR BROKERAGE CO., LTD.

FINANCIAL SERVICES

GOLDEN INSURANCE BROKERS CO., LTD.

FINANCIAL SERVICES

IV TECHNOLOGIES CO., LTD.

MANUFACTURING

PRESIDENT INFORMATION CORP.

TELECOMMUNICATIONS & ICT

INSPIRATIONAL BRAND CATEGORY

COMPANY

INDUSTRY

ARTISTIC BIOMEDICAL LIMITED COMPANY

HEALTHCARE, PHARMACEUTICAL & BIOTECHNOLOGY

AWESOME GROUP

EDUCATION & TRAINING

CNC-TAKANG CO., LTD.

TRADING & WHOLESALING

CPC CORPORATION, TAIWAN

OIL & GAS

H2U CORPORATION

PROFESSIONAL & BUSINESS SERVICES

NAN HOANG TRAFFIC INSTRUMENT CO., LTD.

MANUFACTURING

WINCOMM CORPORATION

MANUFACTURING

CORPORATE EXCELLENCE CATEGORY

COMPANY

INDUSTRY

ACE EDULINK CO., LTD.

EDUCATION & TRAINING

ALLJACK TECHNOLOGIES, INC.

MANUFACTURING

CHAINSEA INFORMATION INTEGRATION CO., LTD.

TELECOMMUNICATIONS & ICT

EXCELLENCE OPTOELECTRONICS INC.

AUTOMOTIVE

FARADAY TECHNOLOGY CORPORATION

SEMICONDUCTOR

GREENFILTEC.LTD

SEMICONDUCTOR

GREENYN BIOTECHNOLOGY CO., LTD.

MANUFACTURING

HUSHAN AUTOPARTS INC.

AUTOMOTIVE

NEFFUL INTERNATIONAL HOLDINGS PTE. LTD., TAIWAN BRANCH

DIRECT SELLING

PACIFIC SOGO DEPARTMENT STORES CO., LTD.

RETAIL

RAYDIUM SEMICONDUCTOR CORPORATION

SEMICONDUCTOR

SHIN KONG LIFE INSURANCE CO., LTD.

FINANCIAL SERVICES

TAI FUNG TRADING CO., LTD.

ENERGY

UNIVERGY SOLAR

ENERGY

YUAN JIN CHUANG ENTERPRISE CO., LTD.

FOOD & BEVERAGE

About Enterprise Asia

Enterprise Asia is a non-governmental organization in pursuit of creating an Asia that is rich in entrepreneurship as an engine towards sustainable and progressive economic and social development within a world of economic equality. Its two pillars of existence are an investment in people and responsible entrepreneurship. Enterprise Asia works with governments, NGOs, and other organizations to promote competitiveness and entrepreneurial development, uplift the economic status of people across Asia, and ensure a legacy of hope, innovation, and courage for future generations. Please visit www.enterpriseasia.org for more information.

About Asia Pacific Enterprise Awards

Launched in 2007, the Asia Pacific Enterprise Awards is the region's most prestigious award for outstanding entrepreneurship, continuous innovation, and sustainable leadership. The Award provides a platform for companies and governments to recognize entrepreneurial excellence, hence spurring greater innovation, fair business practices, and growth in entrepreneurship. As a regional award, it groups together leading entrepreneurs as a powerful voice for entrepreneurship and serves as a by-invitation-only networking powerhouse. The program has grown to encompass 16 countries/ regions and markets all over Asia. For further information, please visit www.apea.asia.

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Asia Pacific Enterprise Awards (APEA) 2024 Celebrates Taiwan's Trailblazers in Inclusive Entrepreneurship

Asia Pacific Enterprise Awards (APEA) 2024 Celebrates Taiwan's Trailblazers in Inclusive Entrepreneurship

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