Byondis Appoints Louis Denis, M.D., as Chief Medical Officer

NIJMEGEN, The Netherlands--(BUSINESS WIRE)--Nov 19, 2024--

Byondis B.V., an independent clinical stage biopharmaceutical company creating innovative targeted medicines for patients with cancer, announces the appointment of Louis Denis, M.D. as Chief Medical Officer. Dr. Denis brings more than 30 years of clinical development leadership and oncology expertise to Byondis.

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“We are excited that Louis has joined the Byondis team. Building on our successful proprietary drug discovery, research and development and in-house CMC capabilities, his proven track record and expertise in cancer drug development will be invaluable to rapidly advance our pipeline through the clinic and ultimately reach patients,” said Byondis’ Founder and CEO Jacques Lemmens, Ph.D.

"Byondis is uniquely positioned to make meaningful contributions to cancer care based on its deep scientific knowledge, strong research capabilities and broad pipeline of new antibody-drug conjugates and antibody-based therapeutics,” said Dr. Denis. “I look forward to working together to advance and deliver the next generation of targeted cancer treatments for patients.”

Prior to joining Byondis, Dr. Denis was the Chief Medical Officer at Verastem Oncology and at Asana BioSciences since 2015. Previously, Dr. Denis held various leadership roles in Oncology clinical development and medical affairs at Boehringer Ingelheim and Pfizer. Dr. Denis received his M.D. from the Vrije Universiteit Brussel, Belgium, and did his post-doctoral fellowships in Internal Medicine/Medical Oncology at Middelheim Hospital, Antwerp; the Rotterdam Cancer Institute, The Netherlands; and the Institute for Drug Development, Cancer Therapy and Research Center, San Antonio, Texas.

About Byondis

Driven to improve patients’ lives, Byondis is an independent clinical stage biopharmaceutical research and development company creating innovative targeted medicines for cancer. The company is developing new biological entities (NBEs) focusing on antibody-drug conjugates and antibody-based therapeutics.

Byondis’ broad development portfolio comprises preclinical and early-stage clinical programs. The product candidates combine Byondis’ expertise in linker-drug (LD) technology, antibody-drug conjugation, targeted cytotoxic therapy, immunology, and monoclonal antibody (mAb) development. Byondis’ expertise covers all preclinical R&D from early lead finding to production of clinical batches of the selected product candidates, which are all done in-house.

The company has a dedicated team of more than 300 staff working in its state-of-the-art R&D and GMP manufacturing facilities in Nijmegen, the Netherlands. For more information visit www.byondis.com.

Louis Denis, M.D., Chief Medical Officer, Byondis (Photo: Business Wire)

ARLINGTON, Texas (AP) — A piece of the roof at the home of the Dallas Cowboys fell to the field while the retractable portion of it was being opened at least three hours before a 34-10 loss to Houston on Monday night, officials said.

AT&T Stadium was mostly empty when the incident occurred, and team officials said nobody was injured. The roof was closed without incident about an hour later.

Officials said winds gusting to 30 mph during the day contributed to the incident, which was being reviewed to ensure the roof can be opened safely at some point in the future. The roof hasn't been opened for a Cowboys game in their $1.2 billion stadium since the 2022 season.

“I know we opened it long before any fans or anybody is in there,” owner Jerry Jones said after the game. “The reason they do that is to make sure everything is working to avoid those kinds of risks if there’s any fans or anybody in here.”

Jones said there wasn't any risk in going on with the game, which meant a delay or postponement wasn't a consideration.

“They wouldn’t have done this game, or started this game, had there been any risk at all,” Jones said. “Not only the NFL wouldn’t, but I wouldn’t if there was any risk at all. And there was no risk at all when we started the game.”

The arches that support the roof are nearly 300 feet above the field at their highest point. The 80,000-seat venue opened in 2009.

The falling debris came a little more than a week after Dallas receiver CeeDee Lamb said the sun was in his eyes on a throw he didn't react to in the end zone in a 34-6 loss to Philadelphia.

AT&T Stadium has an unusual east-west alignment from end zone to end zone, as opposed to most venues being north-south. On clear days, the sun shines through the large glass windows on the west side during the first half of games that kick off in the afternoon.

There is usually a call for curtains on the west side of the stadium when the sun becomes an issue, but Jones says he won't put up curtains. He says both teams have to deal with the sun.

When AT&T Stadium hosted the Super Bowl in 2011, six workers were injured when ice and snow fell from the roof. The event was plagued by a historic ice storm that gripped the Dallas area for days.

AP NFL: https://apnews.com/hub/nfl

The roof is seen open at AT&T Stadium prior to an NFL football game between the Dallas Cowboys and the Houston Texans, Monday, Nov. 18, 2024, in Arlington. (AP Photo/Jerome Miron)