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NTx Announces Full Commercial Availability of NTxscribe to Broadly Enable RNA Therapies

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NTx Announces Full Commercial Availability of NTxscribe to Broadly Enable RNA Therapies
News

News

NTx Announces Full Commercial Availability of NTxscribe to Broadly Enable RNA Therapies

2025-01-09 22:01 Last Updated At:22:12

RIO RANCHO, N.M.--(BUSINESS WIRE)--Jan 9, 2025--

Nature’s Toolbox (NTx), a life sciences company developing next-generation platforms for RNA and protein manufacturing, today announced the full commercial availability of NTxscribe ®, a benchtop, continuous flow RNA in vitro transcription (IVT) and purification system that brings cost effective and scalable RNA manufacturing to the market.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250109963944/en/

Traditional RNA production methods are costly and complex. This slows clinical innovation, makes it hard to scale production to meet demand, and makes it nearly impossible to produce affordable personalized medicines. NTxscribe solves these challenges with a benchtop system that produces high-yield, high-integrity RNA in continuous flow and can scale seamlessly from small research doses to commercial volumes. NTxscribe produces 10-50 mg of high integrity RNA in two hours, shortening timelines for bringing new therapies and vaccines to market and empowering researchers, biotech, and pharmaceutical companies to make personalized medicine a reality.

“Our team has worked closely with NTx and utilized the innovative NTxscribe system for the last several years,” said John Cooke, MD, Ph.D., Medical Director of the RNA Therapeutics Program at the Houston Methodist DeBakey Heart and Vascular Center. “Through our partnership on a contract from Biomedical Advanced Research and Development Authority (BARDA), we were able to deliver exceptional results in demonstrating how NTxscribe can fulfill the need for a rapidly deployable RNA vaccine manufacturing capability. After seeing the final commercial product at NTx’s recent Scientific Advisory Board session, I believe we are seeing the future of how medicine will be delivered.”

NTxscribe’s small footprint enables rapid deployment even in mobile cleanrooms. Lower infrastructure costs make high-quality RNA production accessible to a wider range of organizations, including smaller labs and startups. NTxscribe also utilizes 100% U.S. made raw materials and enables an end-to-end domestic supply chain for critical biomaterials, in contrast to the current reality of profound dependence on China.

“Traditional biomanufacturing methods have not been able to keep pace with the surge in therapeutic innovation and rise of personalized medicine, and until now, there has not been a solution for the gaps in scalability and quality,” said Jamie Coffin, President and CEO at NTx. “Following our fully subscribed early access program with leading academic medical centers and major biopharma organizations, we are excited to bring NTxscribe to the broader market and help unlock the full potential of RNA therapies by enabling innovation for the future of medicine.”

To learn more about NTxscribe and how NTx can help address different biomanufacturing needs, please schedule a design session here: https://ntxbio.com/reserve.

About NTx

Nature’s Toolbox, Inc. (NTx), based in Rio Rancho, New Mexico, is revolutionizing biomanufacturing with cutting-edge solutions tailored to the demands of modern research and personalized medicine. NTx is developing innovative systems like NTxscribe® and NTxpress® to enable the sustainable production of mRNA and protein therapeutics, offering scalability from personalized doses to mass-market volumes. Discover how NTx is shaping the future of medicine at www.ntxbio.com.

NTx announced the full commercial availability of NTxscribe®, a benchtop, continuous flow RNA in vitro transcription (IVT) and purification system that brings cost effective and scalable RNA manufacturing to the market. (Photo: Business Wire)

NTx announced the full commercial availability of NTxscribe®, a benchtop, continuous flow RNA in vitro transcription (IVT) and purification system that brings cost effective and scalable RNA manufacturing to the market. (Photo: Business Wire)

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Stenlund ends scoring drought to help Utah down slumping Red Wings, 4-2

2025-03-07 10:48 Last Updated At:10:51

DETROIT (AP) — Kevin Stenlund scored the go-ahead goal early in the third period and the Utah Hockey Club handed Detroit its fourth straight loss, 4-2 on Thursday night.

Stenlund scored his first goal in 24 games, while Dylan Guenther, Nick Schmaltz and Lawson Crouse also scored for Utah, which has won four of its last five games. Karel Vejmelka made 38 saves on the same day he signed to a five-year contract extension.

Dylan Larkin and Jonatan Berggren scored first-period goals for the Red Wings. Alex Lyon stopped 15 shots.

Detroit is 1-4-1 in its last six home games.

Utah: Vejmelka's save total included six against the Red Wings' second-ranked power play as Utah killed three penalties.

Red Wings: Carter Mazur's NHL debut lasted only two shifts. Mazur, a 22-year-old forward called up from the American Hockey League's Grand Rapids Griffins, suffered an upper-body injury in the first period and did not return. The Michigan native had a large contingent of family and friends in attendance.

Stenlund's first goal since Jan. 2 came with a fortunate bounce. Michael Kesselring dug the puck away from the boards. It struck a defenseman's skate and bounced onto the stick of Stenlund, who scored from the right circle to give Utah a 3-2 lead at 2:55 of the third.

Utah first line forward Clayton Keller reached the 300 career assist mark on Schmaltz's second-period, power-play goal. Keller has 48 assists this season and 13 points in his last eight games.

Utah visits Chicago on Friday night while the Red Wings visit Washington on Friday night.

AP NHL: https://apnews.com/hub/nhl

Detroit Red Wings left wing Lucas Raymond (23) celebrates his goal with Dylan Larkin (71) in the third period of an NHL hockey game against the Minnesota Wild, Saturday, Feb. 22, 2025, in Detroit. (AP Photo/Paul Sancya)

Detroit Red Wings left wing Lucas Raymond (23) celebrates his goal with Dylan Larkin (71) in the third period of an NHL hockey game against the Minnesota Wild, Saturday, Feb. 22, 2025, in Detroit. (AP Photo/Paul Sancya)

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